PEG Modifier Detection Kit

Kit to detect antibodies to polyethylene glycol (PEG) and PEG modifications of synthetic polymers.

We developed an ELISA kit that can detect anti-PEG antibodies (IgG and IgM) in serum using monoclonal antibodies purified from a hybridoma that produces anti-PEG antibodies, which was originally developed by us. The kit can detect anti-PEG antibodies using human clinical specimens, and is useful in cases where anti-PEG antibodies are suspected to be present in the blood, such as failure of treatment with PEGylated drugs or allergic reactions such as anaphylaxis-like reactions after administration of PEGylated drugs. We also offer a kit to quantify the concentration of PEG modifier in blood by sandwich ELISA with monoclonal antibody.